Paintsville/Johnson Co. 911 received a call around 2:09 PM Wednesday afternoon about a structure fire located on Lower Twin Branch.
According to the caller, heavy smoke could be seen coming from the residence.
Dispatch toned out members of Rockhouse Fire and Rescue to the scene and W.R. Castle Fire and Rescue for mutual aid.
Once on scene, firefighters could see flames coming from the residence.
Efforts to save the structure was made for nearly 3 hours, but the structure was said to be a total loss.
No injuries were reported during the fire.
A cause of the fire has not yet been released as of news time.